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Filtered Search Results
Medchemexpress LLC H-Val-Pro-Pro-OH | 58872-39-2 | MFCD08458654 | 99.9% | 311.38 | C15H25N3O4 | 5 MG
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H-Val-Pro-Pro-OH is a milk-derived tripeptide that inhibits angiotensin I-converting enzyme (ACE) with a reported IC50 of approximately 9 μM. It has been reported to exhibit anti-hypertensive and anti-inflammatory effects, and to enhance GLUT4 expression and glucose uptake in adipocyte models. The compound is supplied as a white to off-white solid with high purity and recommended frozen storage for long-term stability.
- Inhibits angiotensin I-converting enzyme (ACE) with IC50 ≈ 9 μM.
- Reported anti-hypertensive and anti-inflammatory activity.
- Enhances GLUT4 expression and restores glucose uptake in adipocytes.
- High purity solid suitable for biochemical and cellular assays.
- Soluble in DMSO (12.5 mg/mL) with sonication and warming to 60°C.
- Stable under recommended frozen storage conditions for long-term use.
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Medchemexpress LLC O-Methyl-D-valine hydrochloride | 7146-15-8 | 98.0% | C6H14ClNO2 | 500 G
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O-Methyl-D-valine hydrochloride is a valine derivative. It is for research use only. Amino acids and amino acid derivatives, including O-Methyl-D-valine hydrochloride, are commercially used as ergogenic supplements.
- Influences anabolic hormone secretion
- Provides fuel supply during exercise
- Supports mental performance during stress-related tasks
- Helps prevent exercise-induced muscle damage
- Recognized as beneficial ergogenic dietary substances
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Medchemexpress LLC MC-Val-Cit-PAB-MMAF | 863971-17-9 | 99.3% | 1330.61 | 50 MG
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MC-Val-Cit-PAB-MMAF (Vc-MMAF) is a drug-linker conjugate for Antibody-Drug Conjugate (ADC) applications. It utilizes the tubulin inhibitor MMAF, linked via a cathepsin cleavable MC-Val-Cit-PAB. This conjugate has demonstrated antitumor activity.
- Used in antibody-drug conjugate (ADC) applications.
- Utilizes the tubulin inhibitor MMAF.
- Linked via a cathepsin cleavable MC-Val-Cit-PAB.
- Demonstrates antitumor activity.
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Medchemexpress LLC Val-Cit-PAB-MMAF sodium | 863971-56-6 | 98.4% | 1159.39 | C58H91N10NaO13 | 10 MG
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Val-Cit-PAB-MMAF sodium is an antibody-drug conjugate (ADC) agent-linker conjugate that couples the Val-Cit-PAB peptide linker to the tubulin inhibitor MMAF. It is supplied as a sodium salt, provided as a solid, and is intended for ADC research and linker-payload development.
- High purity (98.4%).
- Supplied as a solid; soluble in DMSO at 50 mg/mL (requires ultrasonic treatment).
- Stable when stored under nitrogen: 4°C for solid; in solution, -80°C for 6 months, -20°C for 1 month.
- Available in small research sizes, e.g., 10 mg.
- Contains the Val-Cit-PAB peptide linker conjugated to the MMAF payload.
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Cayman Chemical Cyclo L-Pro-L-Val 50mg
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A diketopiperazine; active against S. aureus and B. subtilis (MICs = 16.3 and 18.2 UG/ml, respectively); modulates LuxR-dependent quorum sensing systems but not lacZ-based reporter fusions; inhibits activation of a LuxR-dependent E. coli biosensor by 3-oxo-hexanoyl-homoserine lactone (IC50 = 0.4 mM) and activates violacein pigment production in the LuxR-dependent C. violaceum acyl homoserine lactone reporter strain CV026
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Chem-Impex International, Inc. L-Norvaline | 6600-40-4 | MFCD00064421 | 25G
L-Norvaline, 6600-40-4, MFCD00064421, 25G
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Chem-Impex International, Inc. Fmoc-L-valine | 68858-20-8 | MFCD00037124 | 25G
Fmoc-L-valine, 68858-20-8, MFCD00037124, 25G
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Chem-Impex International, Inc. Fmoc-D-norvaline | 144701-24-6 | MFCD00155640 | 25G
Fmoc-D-norvaline, 144701-24-6, MFCD00155640, 25G
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Medchemexpress LLC Boc-Val-Ala-PAB-PNP | 1884578-00-0 | ≥98.0% | 558.58 | C27H34N4O9 | 50 MG
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Boc-Val-Ala-PAB-PNP is a cleavable antibody-drug conjugate (ADC) linker used to connect cytotoxic payloads to antibodies during ADC synthesis. It is supplied as a protected Val-Ala-PAB derivative with a para-nitrophenyl (PNP) activated group for conjugation chemistry and is intended for research use only.
- Cleavable Val-Ala peptide linker for cathepsin-mediated release.
- PNP-activated ester enables efficient coupling to payloads.
- High purity suitable for research (≥98.0%).
- Stable powder storage at -20°C for long-term preservation.
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Medchemexpress LLC H-DL-Val-OMe.HCl | 5619-05-6 | ≥98.0% | 167.63 | 500 G
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H-DL-Val-OMe.HCl is a valine derivative. Amino acids and amino acid derivatives are commercially used as ergogenic supplements, influencing anabolic hormone secretion, fuel supply during exercise, mental performance during stress-related tasks, and preventing exercise-induced muscle damage. They are recognized as beneficial ergogenic dietary substances.
- Valine derivative
- Can be used as an ergogenic supplement
- Influences the secretion of anabolic hormones
- Supplies fuel during exercise
- Improves mental performance during stress-related tasks
- Prevents exercise-induced muscle damage
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Apexbio Technology LLC Mc-Val-Cit-PABC-PNP 159857-81-5 10mg
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Mc-Val-Cit-PABC-PNP (159857-81-5) is a peptide-based linker commonly utilized in the development of antibody-drug conjugates (ADCs) It is designed to facilitate site-specific payload release through protease-mediated cleavage especially by lysosomal cathepsin enzymes enabling targeted drug delivery within tumor cells Mc-Val-Cit-PABC-PNP exerts its biological function by being recognized and cleaved upon internalization in cancer cells resulting in the selective release of conjugated cytotoxic agents Based on these properties Mc-Val-Cit-PABC-PNP holds research potential in the synthesis and optimization of ADCs for targeted cancer therapies
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Medchemexpress LLC Azido-PEG(4)-Val-Cit-PAB-PNP | 1869126-60-2 | C₃₆H₅₁N₉O₁₃ | 25 MG
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Azido-PEG(4)-Val-Cit-PAB-PNP is a cleavable peptide Antibody-Drug Conjugate (ADC) linker. It functions as a click chemistry reagent, containing an azide group that enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules, and ring strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups.
- Cleavable peptide ADC linker
- Functions as a click chemistry reagent
- Contains an azide group
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Enables ring strain-promoted alkyne-azide cycloaddition (SPAAC)
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Medchemexpress LLC Fmoc-D-N-Me-Val-OH | 103478-58-6 | 99.3% | 353.42 | 25 G
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Fmoc-D-N-Me-Val-OH is a valine derivative. Amino acids and amino acid derivatives have been commercially used as ergogenic supplements, influencing anabolic hormone secretion, fuel supply during exercise, mental performance during stress, and prevention of exercise-induced muscle damage. They are recognized as beneficial ergogenic dietary substances.
- Influences anabolic hormone secretion
- Provides fuel during exercise
- Supports mental performance during stress
- Aids in preventing exercise-induced muscle damage
- High purity of 99.28%
- Appears as a white to off-white solid
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules 870487-10-8 | Boc-Val-Cit-PAB-PNP | Ambeed | MFCD22417105 | 644.682 | C30H40N6O10 | 98.000 | CC(C)[C@H](NC(=O)OC(C)(C)C)C(=O)N[C@@H](CCCNC(N)=O)C(=O)Nc1ccc(COC(=O)Oc2ccc(cc2)[N+]([O-])=O)cc1 | 5mg | 816453519
Boc-Val-Cit-PAB-PNP | Ambeed | 870487-10-8 | MFCD22417105 | 644.682 | C30H40N6O10 | 98.000 | CC(C)[C@H](NC(=O)OC(C)(C)C)C(=O)N[C@@H](CCCNC(N)=O)C(=O)Nc1ccc(COC(=O)Oc2ccc(cc2)[N+]([O-])=O)cc1 | 5mg | 816453519
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Medchemexpress LLC MC-Val-Cit-PAB-MMAF | 863971-17-9 | 99.25% | 1330.61 | 25 MG
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MC-Val-Cit-PAB-MMAF (Vc-MMAF) is a drug-linker conjugate for ADC, utilizing the tubulin inhibitor, MMAF (HY-15579), linked via cathepsin cleavable MC-Val-Cit-PAB (HY-78738). It exhibits antitumor activity.
- Drug-linker conjugate for ADC.
- Uses tubulin inhibitor MMAF.
- Linked via cathepsin cleavable MC-Val-Cit-PAB.
- Shows antitumor activity.
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